Cacao: Brain Power
Wake-up your body and brain with Cacao Brain Power. This muesli will give you extra boost with every plant-packed mouthful. Find out how in our ingredient table below!
Artisan Muesli made in Byron Bay
ORGANIC | PALEO | GLUTEN, DAIRY & GM FREE | VEGAN
This is a product for all those who would like to reap to benefit of the exciting chemicals in cocoa, without having to indulge in a sneaky early morning chocolate. From the dopamine boost in cacao, to the ginger’s serotonin tickle, this is a blend of energising plant compounds designed for short-term focus, and long term benefit.
Cocoa extracts have been noted in vitro to downregulate inflammatory cytokines from macrophages including MCP-1, TNF-α, and IL-6 with a potency greater than a similar concentration of pure (-)-epicatechin (with similar antiinflammatory effects noted in whole blood). Other studies have noted the isolated cocoa constituent clovamide has similar effects in LPS-stimulated macrophages. In the absence of LPS or other pro-inflammatory stimuli, procyanidins from cocoa have been noted to possess the ability to increase the secretion of IL-1, IL-6, and TNF-α in PMBCs, where the longer chain flavanols seem to be more potent.
It has been suggested that cocoa constituents may suppress macrophage activity via their intrinsic antioxidant action, since inflammatory pathways tend to be REDOX-sensitive, and antioxidants in general have been shown to suppress the activation of macrophages. Indeed, NF-kB, which plays a prominent role in macrophage activation, is suppressed by antioxidants. Moreover, (-)-epicatechin has been shown to suppress NF-kB..
(-)-epicatechin and other flavanols in cocoa may limit macrophage activation via their intrinsic antioxidant activity.
Oral ingestion of 1mg/kg (-)-epicatechin twice daily in one year-old mice (C57BL/6N) for 15 days alongside exercise caused improvements in duration and distance until failure relative to exercise alone. (-)-
In another study in sedentary middle aged adults (42 years of age) 1mg/kg (-)-epicatechin twice daily increased grip strength by 7% relative to baseline, although this was not compared to a placebo control.
Aortic pulse wave velocity (PWV) is a measure used to assess aortic stiffness, a hardening of the aorta from calcification which is the long-term target of Vitamin K for cardiovascular health and is a good independent predictor of all-cause mortality at all ages.
When testing cocoa in otherwise healthy adults on this parameter, 10g of 75% dark chocolate daily for a month has resulted in a decrease in PWV of 5% (6.13+/-0.41m/s to 5.83+/-0.53m/s) which is an effect not observed with acute usage of a higher dose of cocoa (100 grams) in the same demographic.
Some studies have indicated that cocoa may increase nitric oxide production. Ingestion of dark chocolate (30g of 70% cocoa) in prehypertensive subjects can increase the amount of nitric oxide in serum within 15 days by 54% as assessed by serum biomarkers. One study has also noted a reduction in vascular arginase activity, the enzyme that degrades Arginine, thought to result in an increase in L-arginine availability and hence an greater capacity to synthesize nitric oxide.
(-)-Epicatechin in cocoa powder has been shown to enhance oxidative metabolism and mitochondrial function in addition to promoting mitochondrial biogenesis in animal models. Preliminary evidence suggests this may also occur in humans.
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450g Jar, 450g Eco Refill Bag, 1kg Bag, 200g Snack Bag